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PhD position in Infection Biology at Otto von Guericke Univ Germany

The Institute of Experimental Internal Medicine offers: PhD position (m/f) (TVL-E13/2) in an interdisciplinary project of Infection Biology.

Helicobacter pylori, the etiological agent of several human gastric diseases, induce the transcription factor NF-kappaB in colonized epithelial cells leading to the release of pro-inflammatory mediators.

The project is based on recent discoveries of novel signaling components of the NF-kappaB signaling pathway in mammalian cells. The successful applicants will define the role of this novel signaling molecules in Helicobacter pylori infection model by integrating molecularbiological, physiological and cell biological analysis.

The research program of the institute encompasses scientific projects on the regulation of the NF-kappaB signal transduction in the pathophysiology of inflammation and tumor biology (e.g. differentiation and cell cycle control). Here, the molecular and cell biological mechanisms of the intracellular signal transmission are of special interest. The institute allows an internationally competitive research by providing state of the art technologies in protein analysis, mass spectrometry and microscopy.

The institute coordinates and participates in a variety of coordinated programs funded by the German Research Foundation (GRK1167, SFB854, SFB779, SPP1365 and FOR521), the Federal Ministry of Education and Research (SysTec) and the European Union (Marie Curie Research Training Network).

Further, the institute is member of the interdisciplinary “Research Center Dynamic Systems: Biosystems Engineering (CDS)” funded by the Federal State of Saxony-Anhalt within the “Excellence Program” and the “Magdeburg Center of Systems Biology (MaCS)” funded by the Federal Ministry of Education and Research within the „FORSYS“ program “Research Units in Systems Biology”.
The Otto von Guericke University wishes to increase the proportion of female academic personnel. Women are therefore explicitly encouraged to apply. Handicapped persons with equivalent qualification will be given preference.

How to apply:

Please send a motivation letter, CV and two references as PDF-file to Prof. Dr. M. Naumann (naumann@med.ovgu.de) until the end of April 2011.

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